Molecular Mechanisms In Proliferative Skin Disease

Molecular Mechanisms of Skin Diseases

Molecular mechanisms of skin ageing.

Cutaneous ageing is a complex biological phenomenon consisting of two components; intrinsic ageing, which is largely genetically determined and extrinsic ageing caused by environmental exposure, primarily UV light. In sun-exposed areas, these two processes are superimposed. The process of intrinsic skin ageing resembles that seen in most internal organs and is thought to involve decreased proli...

Evaluation of neuroprotective effects of cobalamin (vitamin B12) in Parkinson's disease - Investigation of molecular mechanisms

‌Background & objectives: Parkinson's disease is one of the most common neurodegenerative diseases that its prevalence has increased in recent years. Although many efforts have been made to treat this disease, so far, no therapeutic approach has been found that can stop the destruction of dopaminergic cells in the substantia nigra. The aim of the present study was to investigate the effect of v...

[Molecular mechanisms in Alzheimer's disease].

15.1 Introduction Alzheimer's disease (AD), a progressive neurovegetative disorder of the central nervous system and a leading cause of dementia, is partially caused by genetic changes. The molecular mechanisms and hypothesis of AD is very complex. The key event leading to AD appears to be the formation of a peptide known as amyloid beta (Aß) which clusters into amyloid plaques or senile plaque...

Molecular mechanisms in Behçet's disease.

M uch is still unknown about the aetiopathogenesis of Behçet’s disease, although genetic, infectious, and autoimmune components are all believed to be involved. The distribution and wide variation in relative risk of HLA-B51 is well documented and appears to support the presence of other, non-genetic risk factors for Behçet’s disease. The contribution of HLA-B51 to the overall genetic susceptib...